Ornidaz

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Ornidaz

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ORNIDAZ (Orindazole) 500 mg 10 tablet(s) for 23 L.E. 3 table(s) for 7 L.E manufactured by Chemipharm.

ORNIDAZ (Orindazole) is effective against Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia (Giardia intestinalis), and also against certain anaerobic bacteria such as Bacteroides and Clostridium spp.,

Fusobacterium spp., and anaerobic cocci.

Dosage and Administration

Standard Dosage

The tablets must always be taken after meals.

Trichomoniasis

There are two possible therapeutic regimens: Single-dose therapy (for acute trichomoniasis); five-day therapy (for chronic forms of trichomoniasis). The tablets should be taken after meals.

(a) Single dose therapy

(b) Five day therapy

Type of Treatment	Daily Dosage (500 mg tablets)
(a) Single-dose	3 tablets in the evening
(b) Five-day therapy	2 tablets (1 tablet mornings and evenings)

In all cases, the sexual partner should also be treated using the same oral dosage so as to avoid reinfection.

The dosage for children is 25 mg per kg bodyweight per day, given in a single dose.

Amoebiasis

(a) Three-day treatment of patients with amoebic dysentery

(b) Five-to-ten-day treatment for all forms of amoebiasis

Duration of Treatment	Daily Dosage
Duration of Treatment	Adults and children over 35 kg	Children up to 35 kg
a) Three days	3 tablets in one evening dose Over 60 kg bodyweight: 4 tablets ( 2 tablets mornings and evenings)	125 mg (1/4 tablet) per 3 kg bodyweight in one dose (equivalent to 40 mg per kg)
b) Five to ten days	2 tablets (1 tablet mornings and evenings)	125 mg (1/4 tablet) per 5 kg bodyweight in one dose (equivalent to 25 mg per kg)

Giardiasis (lambliasis)

Duration of Treatment	Daily dosage
Duration of Treatment	Adults and children over 35 kg	Children up to 35 kg
One to two days	3 tablets in the evening in one dose	125 mg (1/4 tablet) per 3 kg bodyweight in one dose (equivalent to 40 mg per kg)

Anaerobic Infections

Prophylaxis: 1500 mg orally, 12 hours before surgery then 500 mg 12-hourly for 3 to 5 days postoperatively.

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